摘要

目的 探析无肝素化人工肝血浆置换治疗肝衰竭患者的护理及安全性。方法 将2024年5月-2025年5月在我院接受血浆置换治疗的肝衰竭患者46例纳入此次研究，依照信封法随机分成参考组（接受常规加用肝素的血浆置换治疗）与实验组（接受无肝素化人工肝血浆置换治疗及注射泵持续进行生理盐水冲洗分离器及管路），各23例。对比两组的护理效果。结果 护理后，实验组的肝功能指标均更优（P<0.05）；在不良反应发生率上，实验组更低（P<0.05）。结论 无肝素化人工肝血浆置换治疗肝衰竭并配合护理干预，能有效改善患者肝功能，降低不良反应发生率。

关键词

无肝素化人工肝血浆置换；肝衰竭；护理；安全性

Abstract

Objective To explore the nursing and safety of heparin free artificial liver plasma exchange therapy for patients with liver failure.
Methods 46 patients with liver failure who received plasma exchange treatment in our hospital from May 2024 to May 2025 were included in this study. They were randomly divided into a reference group (receiving conventional plasma exchange treatment with heparin) and an experimental group (receiving non heparinized artificial liver plasma exchange treatment and continuous flushing of the separator and tubing with saline injection pump) using the envelope method, with 23 cases in each group. Compare the nursing effects of the two groups.
Results After nursing, the liver function indicators of the experimental group were all better (P<0.05); The experimental group had a lower incidence of adverse reactions (P<0.05).
Conclusion   Heparin free artificial liver plasma exchange therapy combined with nursing intervention can effectively improve liver function and reduce the incidence of adverse reactions in patients with liver failure.

Key words

Heparin free artificial liver plasma exchange; Liver failure; Nursing; Safety